Journal Article
Title | Relationship between bone GLA-protein (BGP) and calcidiol (25-hydroxycalciferol) in serum of breast-fed infants. |
Publication Type | Journal Article |
Authors | Gruson, M, M. Cancela, L, Denne, MA, Miravet, L |
Year of Publication | 1986 |
Journal | Endocrinol Exp |
Volume | 20 |
Issue | 2-3 |
Date Published | 1986 Aug |
Pagination | 329-34 |
ISSN | 0013-7200 |
Keywords | 25-Hydroxyvitamin D 2, Alkaline Phosphatase, Bone and Bones, Breast Feeding, Calcitriol, Calcium, Calcium-Binding Proteins, Ergocalciferols, Female, Humans, Infant, Newborn, Lactation, Osteocalcin, Phosphorus, Pregnancy |
Abstract | The aim of this investigation was to study the bone metabolism in early infancy by establishing the relationship between serum osteocalcin levels and the hormonal vitamin D status of exclusively breast-fed infants during their first month of life. Calcium, phosphorus, alkaline phosphatase, 25-hydroxycalciferol (calcidiol), 1,25-dihydroxycalciferol (calcitriol) and osteocalcin (BGP or GLA-protein) were measured in 22 healthy lactating women and their paired breast-fed infants before and after supplementation (400 IU vitamin D per day). Prior to supplementation calcidiol, calcitriol and osteocalcin remained unchanged. Following supplementation there was an increase in all the parameters with the exception of calcitriol. The administration of vitamin D to breast-fed infants should in fact have an effect on bone activity as reflected by the increase in osteocalcin levels. |
Sapientia | |
Alternate Journal | Endocrinol. Exp. |
PubMed ID | 3489605 |