Disruption of gut integrity and permeability contributes to enteritis in a fish-parasite model: a story told from serum metabolomics

Sitjà-Bobadilla, Ariadna; Gil-Solsona, Rubén; Estensoro, Itziar; Piazzon, M. Carla; Martos-Sitcha, Juan Antonio; Picard-Sánchez, Amparo; Fuentes, Juan; Sancho, Juan Vicente; Calduch-Giner, Josep A.; Hernández, Félix; Pérez-Sánchez, Jaume

Juan Fuentes

Position

Senior Researcher

Academic Degree

Doutoramento

Group

Comparative Endocrinology and Integrative Biology

Based at

Faro, Gambelas Campus, UAlg

Office Nr

Building 8 Room 3.19 Lab: Room: 3.32

Extension

Office: 7203 Lab: 7134

jfuentes@ualg.pt

Keywords

Comparative Physiology, Endocrinology

ORCID ID

ResearchGate

Organiza

Main Info

Born and raised a fisherman I became a comparative physiologist with special interest in adaption physiology and osmoregulation in marine and euryhaline fish. My research program uses an integrative multilevel approach through whole animal in vivo and in vitro studies, epithelial electrophysiology, cellular and molecular techniques

Researchgate

Scholar

Projects

Projects Coordination

	Title	Coordinator	Start	End	Financiamento	Budget CCMAR
Time4Success	Improve Atlantic salmon robustness in freshwater phase through training and feeding to a successfully timed sea transfer.	Juan Fuentes	06/2021	05/2024	RCN - Research Council of Norway	127243k€
CARIOCA	PhysiologiCAl Response of fIsh to OCean Acidification.	Juan Fuentes	04/2016	03/2019	FCT - Fundação para a Ciência e Tecnologia	199k€
CAFE	Fish Hormones and the Ocean Carbon Cycle	Juan Fuentes	05/2013	10/2015	FCT - Fundação para a Ciência e Tecnologia	195k€
BICA	Biomineralização no intestino dos peixes marinhos: uma perspective endócrina	Juan Fuentes	01/2010	12/2012	FCT - Fundação para a Ciência e Tecnologia	165k€
DOURADA	Stanniocalcin na dourada: interacção com factores hipercalcémicos no balanço do cálcio	Juan Fuentes	06/2005	06/2008	FCT - Fundação para a Ciência e Tecnologia	75k€
CALCIUM	Physiology of PTHrP in fish, relevance to calcium balance of an unique hypercalcemic factor.	Juan Fuentes	01/2005	02/2008	FCT - Fundação para a Ciência e Tecnologia	50k€

Activities

Type of Event

Seminar

CCMAR Seminars: Fish in a high CO2 ocean

Next wednesday, October 25th, at 1:30 pm on Amph. -1.8 (bdg 8).

Group

Comparative Endocrinology and Integrative Biology

October 25, 2017

Anf. - 1.8 ( Bdg 8) - Gambelas Campus UAlg

Type of Event

Seminar

CCMAR Seminars: Skeletal anomalies in teleosts: the case of Senegalese sole

Next thursday, November 2nd, at 1:30 pm on Amph. B (CP).

Group

Comparative Endocrinology and Integrative Biology

November 2, 2017

Anf.B ( CP) - Gambelas Campus UAlg

Type of Event

Seminar

CCMAR Seminars: FISHETHOBASE: an open access database on fish ethology and welfare

Next week, November 8nd, at 1:30 pm on Amph. 1.8 (bd8).

Group

Comparative Endocrinology and Integrative Biology

Fish Ethology and Welfare

November 8, 2017

Anf.1.8 ( bd 8) - Gambelas Campus UAlg

Type of Event

Other Events

PhD Thesis Presentation

19 April 2022 13:00 - Alexandra Alves Thesis - Ocean acidification: Physiological response from fish to cell Jury: María Jesús Delgado Saavedra - Universidad Complutense de Madrid, Juan Antonio...

Group

Comparative Endocrinology and Integrative Biology

April 19, 2022

Online | Zoom platform

News

Novo superaditivo para rações de peixes do futuro

Investigadores do Centro de Ciências do Mar (CCMAR) em cooperação com o CSIC (Espanha) concluíram que os ingredientes utilizados em Aquacultura podem ser substituídos por ingredientes de origem vegetal, sem que isso prejudique o crescimento do pescado ou comprometa a qualidade do mesmo. É mais um passo que a ciência dá no caminho da aquacultura sustentável.

We received two groups of high-school students with very special environmental projects. Always a pleasure to meet young people with good ideas!

Publications

Selected Publications

Ruiz-Jarabo I, Gregório SF, Gaetano P, Trischitta F, Fuentes J. High rates of intestinal bicarbonate secretion in seawater tilapia (Oreochromis mossambicus). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 2017. doi:10.1016/j.cbpa.2017.02.022

Ruiz-Jarabo I, Barany A, Jerez-Cepa I, Mancera JMiguel, Fuentes J. Intestinal response to salinity challenge in the Senegalese sole (Solea senegalensis). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 2017;204:57 - 64. doi:10.1016/j.cbpa.2016.11.009

Ruiz-Jarabo I, González-Wevar CA, Oyarzún R, et al. Isolation Driven Divergence in Osmoregulation in Galaxias maculatus (Jenyns, 1848) (Actinopterygii: Osmeriformes). PLoS One. 2016;11(5):e0154766. doi:10.1371/journal.pone.0154766

Gregório SF, Carvalho ESM, Campinho MA, Power DM, Canario AVM, Fuentes J. Endocrine regulation of carbonate precipitate formation in marine fish intestine by stanniocalcin and PTHrP. J Exp Biol. 2014;217(Pt 9):1555-62. doi:10.1242/jeb.098517

Martos-Sitcha JAntonio, Campinho MA, Mancera JMiguel, Martínez-Rodríguez G, Fuentes J. Vasotocin and isotocin regulate aquaporin 1 function in the sea bream. J Exp Biol. 2015;218(Pt 5):684-93. doi:10.1242/jeb.114546

Martos-Sitcha JAntonio, MartínezRodríguez G, Mancera JMiguel, Fuentes J. AVT and IT regulate ion transport across the opercular epithelium of killifish (Fundulus heteroclitus) and gilthead sea bream (Sparus aurata). Comp Biochem Physiol A Mol Integr Physiol. 2015;182:93-101. doi:10.1016/j.cbpa.2014.12.027

Fuentes J, Ribeiro L, Aragão C. Bile salts regulate ion transport in the intestine of Senegalese sole. Aquaculture. 2018;495:842 - 848. doi:10.1016/j.aquaculture.2018.06.050

Gumerova N, Krivosudský L, Fraqueza G, et al. The P-type ATPase inhibiting potential of polyoxotungstates. Metallomics. 2018;10(2):287 - 295. doi:10.1039/C7MT00279C

Sitjà-Bobadilla A, Gil-Solsona R, Estensoro I, et al. Disruption of gut integrity and permeability contributes to enteritis in a fish-parasite model: a story told from serum metabolomics. Parasites & Vectors. 2019;12(1). doi:10.1186/s13071-019-3746-7

Publications

Year of Publication

2017