Journal Article
Título | Conjugates of ovarian steroids, including 17 alpha,20 beta-dihydroxy-4-pregnen-3-one (maturation-inducing steroid), accumulate in the urine of a marine teleost (plaice; Pleuronectes platessa). |
Publication Type | Journal Article |
Authors | Canario, AVM, Scott, AP |
Year of Publication | 1989 |
Journal | J Endocrinol |
Volume | 123 |
Questão | 1 |
Date Published | 1989 Oct |
Pagination | R1-4 |
ISSN | 0022-0795 |
Palavras-chave | Animals, Cortodoxone, Female, Flatfishes, Hydroxyprogesterones, Oogenesis, Ovulation, Radioimmunoassay, Time Factors |
Abstract | Free and conjugated 17 alpha,20 beta-dihydroxy-4-pregnen-3-one (17,20 beta-P), 17 alpha,21-dihydroxy-4-pregnene-3,20-dione (11-deoxycortisol) and 3 alpha,17 alpha,21-trihydroxy-5 beta-pregnan-20-one (3 alpha,17,21-P-5 beta) were measured by radioimmunoassay in matching blood plasma and urine samples from plaice (Pleuronectes platessa) females at several ovarian maturity stages: post-vitellogenesis (IV), final oocyte maturation (V), and ovulation (VI). Free steroids were generally low in all samples. Conjugated steroids were up to 2 orders of magnitude higher in urine than in plasma samples. Conjugated 17,20 beta-P was higher in stage V than in stage IV or VI females. Conjugated 11-deoxycortisol was higher in stage IV and V females. Conjugated 3 alpha,17,21-P-5 beta was higher in stage V and VI females. These results support earlier studies which indicated that 17,20 beta-P was the most likely maturation-inducing steroid (MIS) in plaice, and that the urine might be a vehicle for steroid pheromones synthesized by the gonads. |
Sapientia | |
Alternate Journal | J. Endocrinol. |
PubMed ID | 2809483 |