Transcriptional regulation of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors

Varela, Débora; Conceição, Natércia; Cancela, M. Leonor; Ferreira, Ângela; Marques, Nuno; Silva, Ana Paula; Azevedo, Pedro; Pereira, Salomé; Camacho, Ana; de Jesus, Ilídio; Cancela, M. Leonor

Débora Varela

Position

PhD Student

Academic Degree

Mestrado

Group

Comparative, Adaptive and Functional Skeletal Biology

Coordinator(s)

Leonor Cancela

Natércia Conceição

Thesis title

Epigenetic regulation of ZNF687 in bone cells: towards elucidation of its role in progression of PAGET´s disease towards giant cell tumor

Institution Awarding Degree

Universidade do Algarve

Based at

Faro, Gambelas Campus, UAlg

Phone Nr

+351 289 800051

dcvarela@ualg.pt

Organiza

News

NEW ON BOARD: DÉBORA VARELA

Débora Varela is collaborating with the Bioskel Group at CCMAR.
Welcome Débora!

Publications

Year of Publication
2023	Varela D, Varela T, Conceição N, M. Cancela L. Regulation of human ZNF687, a gene associated with Paget's disease of bone. The International Journal of Biochemistry & Cell Biology. 2023;154:106332. doi:10.1016/j.biocel.2022.106332 Read more about Regulation of human ZNF687, a gene associated with Paget's disease of bone Google Scholar PT DOI
2022	Silva IAL, Varela D, M. Cancela L, Conceição N. Zebrafish optineurin: genomic organization and transcription regulation. Genome. 2022;65(10):513 - 523. doi:10.1139/gen-2022-0019 Read more about Zebrafish optineurin: genomic organization and transcription regulation Google Scholar PT DOI
2022	Varela T, Varela D, Martins G, Conceição N, M. Cancela L. Cdkl5 mutant zebrafish shows skeletal and neuronal alterations mimicking human CDKL5 deficiency disorder. Scientific Reports. 2022;12(1). doi:10.1038/s41598-022-13364-1 Read more about Cdkl5 mutant zebrafish shows skeletal and neuronal alterations mimicking human CDKL5 deficiency disorder Google Scholar PT DOI
2021	Varela D, Varela T, Conceição N, et al. Functional analysis of two novel TBX5 variants present in individuals with Holt–Oram syndrome with different clinical manifestations. Molecular Genetics and Genomics. 2021;296(4):809 - 821. doi:10.1007/s00438-021-01781-2 Read more about Functional analysis of two novel TBX5 variants present in individuals with Holt–Oram syndrome with different clinical manifestations Google Scholar PT DOI
2021	Varela D, Conceição N, M. Cancela L. Transcriptional regulation of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors. Gene. 2021;768:145322. doi:10.1016/j.gene.2020.145322 Read more about Transcriptional regulation of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors Google Scholar PT DOI

Supervising

Leonor Cancela

Natércia Conceição

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