The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance

M. Tarasco; Vincent Laizé; Cardeira, J.; M. Leonor Cancela; Paulo Gavaia; Luis, Nuno; M. Leonor Cancela; Laizé, Vincent; Stainier, Didier Y.R.; Cancela, M. L.; Laizé, Vincent; Laizé, Vincent; Laizé, Vincent

Marco Tarasco

Position

PhD Student

Academic Degree

Mestrado

Group

Comparative, Adaptive and Functional Skeletal Biology

Based at

Faro, Gambelas Campus, UAlg

Office Nr

2.13

Phone Nr

+351 289 800051

Extension

7217

mtarasco@ualg.pt

Keywords

ECM mineralization; Osteogenesis; Cell culture; Screening methods; Zebrafish; Molecular biology; Image analysis

ORCID ID

ResearchGate

Organiza

Main Info

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Marco Tarasco, PhD student in BIOSKEL Lab, is currently studying the effects of environmental pollutants on bone development and regeneration to gain insights into the molecular mechanism underlying osteotoxicity. He has been particularly interested in the development of new tools to better understand the effect of compounds on bone homeostasis and during his master thesis he has developed and optimized the zebrafish operculum as system to screen osteoactive compounds.

Activities

Type of Event

Other Events

Interdisciplinary Approaches in Fish Skeletal Biology (IAFSB) 2018

The fifth conference “Interdisciplinary Approaches in Fish Skeletal Biology” takes place in Tavira, Portugal, April 16-19, 2018.

April 16, 2018 to April 19, 2018

Faro

Type of Event

Other Events

SIBIC 2018

The Centre for Marine Sciences (CCMAR) and the University of Algarve have the pleasure to invite you to SIBIC2018 , the VII Congress of the Iberian Society for Ichthyology, which will take place in...

June 12, 2018 to June 16, 2018

Campus da Penha - UAlg

ATT: Science Communication Course

02-03 November Organization: CCMAR Location: Anf. Verde - Universidade do Algarve - Campus de Gambelas

November 2, 2017 to November 3, 2017

CCMAR - Universidade do Algarve - Campus de Gambelas (Faro)

Publications

Year of Publication
2022	Tarasco M, Gavaia PJ, Bensimon-Brito A, et al. Effects of pristine or contaminated polyethylene microplastics on zebrafish development. Chemosphere. 2022;303:135198. doi:10.1016/j.chemosphere.2022.135198 Read more about Effects of pristine or contaminated polyethylene microplastics on zebrafish development Google Scholar PT DOI
2022	Rosa JT, Tarasco M, Gavaia PJ, M. Cancela L, Laizé V. Screening of Mineralogenic and Osteogenic Compounds in Zebrafish—Tools to Improve Assay Throughput and Data Accuracy. Pharmaceuticals. 2022;15(8):983. doi:10.3390/ph15080983 Read more about Screening of Mineralogenic and Osteogenic Compounds in Zebrafish—Tools to Improve Assay Throughput and Data Accuracy Google Scholar PT DOI
2022	Cardeira-da-Silva J, Bensimon-Brito A, Tarasco M, et al. Fin ray branching is defined by TRAP+ osteolytic tubules in zebrafish. Proceedings of the National Academy of Sciences. 2022;119(48). doi:10.1073/pnas.2209231119 Read more about Fin ray branching is defined by TRAP+ osteolytic tubules in zebrafish Google Scholar PT DOI
2022	Laizé V, Rosa JT, Tarasco M, M. Cancela L. Status, challenges, and perspectives of fish cell culture - Focus on cell lines capable of in vitro mineralization. In: Elsevier; 2022:381 - 404. doi:10.1016/B978-0-12-822273-7.00004-5 Read more about Status, challenges, and perspectives of fish cell culture - Focus on cell lines capable of in vitro mineralization Google Scholar PT DOI
2021	Roberto VP, Surget G, Le Lann K, et al. Antioxidant, mineralogenic and osteogenic activities of Spartina alterniflora and Salicornia fragilis extracts rich in polyphenols. Frontiers in Nutrition. 2021;8:719438. doi:10.3389/fnut.2021.71943810.3389/fnut.2021.719438.s001 Read more about Antioxidant, mineralogenic and osteogenic activities of Spartina alterniflora and Salicornia fragilis extracts rich in polyphenols Google Scholar PT DOI
2021	Tarasco M, Gavaia PJ, Bensimon-Brito A, et al. New insights into benzo[⍺]pyrene osteotoxicity in zebrafish. Ecotoxicology and Environmental Safety. 2021;226:112838. doi:10.1016/j.ecoenv.2021.112838 Read more about New insights into benzo[⍺]pyrene osteotoxicity in zebrafish Google Scholar PT DOI
2020	Tarasco M, Martins G, Gavaia PJ, Bebianno MJ, M. Cancela L, Laizé V. ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts. Zebrafish. 2020;17(1):18-26. doi:10.1089/zeb.2019.1801 Read more about ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts Google Scholar PT DOI
2020	Tarasco M, Cordelières FP, M. Cancela L, Laizé V. ZFBONE: An ImageJ toolset for semi-automatic analysis of zebrafish bone structures. Bone. 2020;138:115480. doi:10.1016/j.bone.2020.115480 Read more about ZFBONE: An ImageJ toolset for semi-automatic analysis of zebrafish bone structures Google Scholar DOI
2019	Tarasco M, Cardeira J, Viegas M, et al. Anti-osteogenic activity of cadmium in zebrafish. Fishes. 2019;4(1):11. doi:10.3390/fishes4010011 Read more about Anti-osteogenic activity of cadmium in zebrafish Google Scholar DOI
2018	Gonçalves R, Tarasco M, Schatzmayr D, Gavaia P. Preliminary Evaluation of Moniliformin as a Potential Threat for Teleosts. Fishes. 2018;3(1):4. doi:10.3390/fishes3010004 Read more about Preliminary Evaluation of Moniliformin as a Potential Threat for Teleosts Google Scholar DOI
2018	Laizé V, Gavaia P, Tarasco M, et al. Osteotoxicity of 3-methylcholanthrene in fish. Ecotoxicology and Environmental Safety. 2018;161:721 - 728. doi:10.1016/j.ecoenv.2018.06.035 Read more about Osteotoxicity of 3-methylcholanthrene in fish Google Scholar DOI
2017	Tarasco M, Laizé V, Cardeira J, M. Cancela L, Gavaia P. The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2017;197:45 - 52. doi:10.1016/j.cbpc.2017.04.006 Read more about The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance Google Scholar DOI

Other Publications

Tarasco, M., Martins, G., Gavaia, P. J., Bebianno, M. J., Cancela, M. L., & Laizé, V. (2019). ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts. Zebrafish.

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