The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance

M. Tarasco; Vincent Laizé; Cardeira, J.; M. Leonor Cancela; Paulo Gavaia; Luis, Nuno; M. Leonor Cancela; Laizé, Vincent; Stainier, Didier Y.R.; Cancela, M. L.; Laizé, Vincent; Laizé, Vincent; Laizé, Vincent

Marco Tarasco

Posição

PhD Student

Grau Académico

Mestrado

Grupo

Comparative, Adaptive and Functional Skeletal Biology

Localização

Faro, Gambelas Campus, UAlg

Gabinete

2.13

Contacto

+351 289 800051

Extensão

7217

mtarasco@ualg.pt

Keywords

ECM mineralization; Osteogenesis; Cell culture; Screening methods; Zebrafish; Molecular biology; Image analysis

ORCID ID

ResearchGate

Organiza

Informação Principal

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Marco Tarasco, PhD student in BIOSKEL Lab, is currently studying the effects of environmental pollutants on bone development and regeneration to gain insights into the molecular mechanism underlying osteotoxicity. He has been particularly interested in the development of new tools to better understand the effect of compounds on bone homeostasis and during his master thesis he has developed and optimized the zebrafish operculum as system to screen osteoactive compounds.

Eventos

Tipo de Evento

Outros Eventos

Interdisciplinary Approaches in Fish Skeletal Biology (IAFSB) 2018

The fifth conference “Interdisciplinary Approaches in Fish Skeletal Biology” takes place in Tavira, Portugal, April 16-19, 2018.

Seg, 16/04/2018 a Qui, 19/04/2018

Local

Faro

Tipo de Evento

Outros Eventos

SIBIC 2018

The Centre for Marine Sciences (CCMAR) and the University of Algarve have the pleasure to invite you to SIBIC2018 , the VII Congress of the Iberian Society for Ichthyology, which will take place in...

Ter, 12/06/2018 a Sáb, 16/06/2018

Local

Campus da Penha - UAlg

ATT: Science Communication Course

02-03 November Organization: CCMAR Location: Anf. Verde - Universidade do Algarve - Campus de Gambelas

Qui, 02/11/2017 a Sex, 03/11/2017

Local

CCMAR - Universidade do Algarve - Campus de Gambelas (Faro)

Publicações

Year of Publication
2022	Tarasco M, Gavaia PJ, Bensimon-Brito A, et al. Effects of pristine or contaminated polyethylene microplastics on zebrafish development. Chemosphere. 2022;303:135198. doi:10.1016/j.chemosphere.2022.135198 Ler mais acerca de Effects of pristine or contaminated polyethylene microplastics on zebrafish development Google Scholar DOI
2022	Rosa JT, Tarasco M, Gavaia PJ, M. Cancela L, Laizé V. Screening of Mineralogenic and Osteogenic Compounds in Zebrafish—Tools to Improve Assay Throughput and Data Accuracy. Pharmaceuticals. 2022;15(8):983. doi:10.3390/ph15080983 Ler mais acerca de Screening of Mineralogenic and Osteogenic Compounds in Zebrafish—Tools to Improve Assay Throughput and Data Accuracy Google Scholar DOI
2022	Cardeira-da-Silva J, Bensimon-Brito A, Tarasco M, et al. Fin ray branching is defined by TRAP+ osteolytic tubules in zebrafish. Proceedings of the National Academy of Sciences. 2022;119(48). doi:10.1073/pnas.2209231119 Ler mais acerca de Fin ray branching is defined by TRAP+ osteolytic tubules in zebrafish Google Scholar DOI
2022	Laizé V, Rosa JT, Tarasco M, M. Cancela L. Status, challenges, and perspectives of fish cell culture - Focus on cell lines capable of in vitro mineralization. In: Elsevier; 2022:381 - 404. doi:10.1016/B978-0-12-822273-7.00004-5 Ler mais acerca de Status, challenges, and perspectives of fish cell culture - Focus on cell lines capable of in vitro mineralization Google Scholar DOI
2021	Roberto VP, Surget G, Le Lann K, et al. Antioxidant, mineralogenic and osteogenic activities of Spartina alterniflora and Salicornia fragilis extracts rich in polyphenols. Frontiers in Nutrition. 2021;8:719438. doi:10.3389/fnut.2021.71943810.3389/fnut.2021.719438.s001 Ler mais acerca de Antioxidant, mineralogenic and osteogenic activities of Spartina alterniflora and Salicornia fragilis extracts rich in polyphenols Google Scholar DOI
2021	Tarasco M, Gavaia PJ, Bensimon-Brito A, et al. New insights into benzo[⍺]pyrene osteotoxicity in zebrafish. Ecotoxicology and Environmental Safety. 2021;226:112838. doi:10.1016/j.ecoenv.2021.112838 Ler mais acerca de New insights into benzo[⍺]pyrene osteotoxicity in zebrafish Google Scholar DOI
2020	Tarasco M, Cordelières FP, M. Cancela L, Laizé V. ZFBONE: An ImageJ toolset for semi-automatic analysis of zebrafish bone structures. Bone. 2020;138:115480. doi:10.1016/j.bone.2020.115480 Ler mais acerca de ZFBONE: An ImageJ toolset for semi-automatic analysis of zebrafish bone structures Google Scholar EN DOI
2020	Tarasco M, Martins G, Gavaia PJ, Bebianno MJ, M. Cancela L, Laizé V. ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts. Zebrafish. 2020;17(1):18-26. doi:10.1089/zeb.2019.1801 Ler mais acerca de ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts Google Scholar DOI
2019	Tarasco M, Cardeira J, Viegas M, et al. Anti-osteogenic activity of cadmium in zebrafish. Fishes. 2019;4(1):11. doi:10.3390/fishes4010011 Ler mais acerca de Anti-osteogenic activity of cadmium in zebrafish Google Scholar DOI
2018	Gonçalves R, Tarasco M, Schatzmayr D, Gavaia P. Preliminary Evaluation of Moniliformin as a Potential Threat for Teleosts. Fishes. 2018;3(1):4. doi:10.3390/fishes3010004 Ler mais acerca de Preliminary Evaluation of Moniliformin as a Potential Threat for Teleosts Google Scholar DOI
2018	Laizé V, Gavaia P, Tarasco M, et al. Osteotoxicity of 3-methylcholanthrene in fish. Ecotoxicology and Environmental Safety. 2018;161:721 - 728. doi:10.1016/j.ecoenv.2018.06.035 Ler mais acerca de Osteotoxicity of 3-methylcholanthrene in fish Google Scholar DOI
2017	Tarasco M, Laizé V, Cardeira J, M. Cancela L, Gavaia P. The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2017;197:45 - 52. doi:10.1016/j.cbpc.2017.04.006 Ler mais acerca de The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance Google Scholar DOI

Other Publications

Tarasco, M., Martins, G., Gavaia, P. J., Bebianno, M. J., Cancela, M. L., & Laizé, V. (2019). ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts. Zebrafish.

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