Isolation and characterization of a stress-inducible Dunaliella salina Lcy-beta gene encoding a functional lycopene beta-cyclase.

Ana A Ramos; Coesel, Sacha; Marques, Ana; Rodrigues, Marta; Baumgartner, Alexandra; Noronha, João; Rauter, Amélia; Brenig, Bertram; João Varela; Mouffouk, Fouzi; Abu-Salah, Khalid M; Ben-Hamadou, Radhouan; João Varela

João Varela

Position

Researcher

Academic Degree

Doutoramento

Group Leader

Marine Biotechnology

Group

Marine Biotechnology

Professor Category

Assistant

Institution

University of Algarve

Based at

Faro, Gambelas Campus, UAlg

jvarela@ualg.pt

ORCID ID

Organiza

Projects

Projects Coordination

	Title	Coordinator	Start	End	Financiamento	Budget CCMAR
Vertical Algas	PRR: Pacto Bioeconomia Azul - Vertical Algas (WP 5)	João Varela, Ester Serrão, Rui Santos	07/2022	12/2025	IAPMEI
SEAWEED	Anaerobic Digestion of Seaweed for Biofuels	João Varela	09/2011	08/2013	Comissão Europeia	211k€
CYANO	Regulação da homeostase do ferro em cianobactérias	João Varela	01/2010	06/2013	FCT - Fundação para a Ciência e Tecnologia	43k€
BOTRYOFUEL	Microalgas hiperprodutoras de hidrocarbonetos	João Varela	07/2007	06/2008	AdI - Agência de Inovação	12k€

Projects Membership

	Title	Coordinator	Start	End	Budget CCMAR	Budget Total
RHE-MEDiation	RHE-MEDiation - Responsive hub for long term governance to destress the Mediterranean Sea from chemical pollution.	Luísa Barreira	06/2023	05/2026		521645k€

Activities

Type of Event

Other Events

PhD Thesis Presentation of Hugo Galvão Pereira

Our PhD candidate Hugo Pereira will defend his thesis, next wednesday.

Group

Marine Biotechnology

July 17, 2019

Anfiteatro Verde, Edf 8

Type of Event

Scientific Gathering

Algas

Este é um workshop é uma iniciativa conjunta do CCMAR, ALLMICROALGAE e PROALGA - Associação Portuguesa de Produtores de Algas para divulgação de atividades de investigação, inovação, sustentabilidade...

November 22, 2019

Auditório da Faculdade de Economia l Edifício 8 l Gambelas Campus

Type of Event

Other Events

MSc Thesis Presentations

Don't miss this week's MSc thesis presentations!

October 20, 2021 to October 21, 2021

Online | Zoom platform

Type of Event

Other Events

MSc Thesis Presentations

Don't miss this week's MSc thesis presentations!

October 28, 2021

Online | Zoom platform

Type of Event

Other Events

MSc Thesis Presentations

2 November 2021 14:30 - Benjamin Schmid Thesis: Assessment of microalgal biomass as a potential feedstock for sustainable, eco-friendly biostimulants and biopesticides in plant production Jury: Rita...

November 2, 2021 to November 5, 2021

Online | Zoom platform

Type of Event

Other Events

MSc Thesis Presentations

Check out this week's thesis defense program and come support the master students and future researchers.

November 10, 2021 to November 11, 2021

Online | Zoom platform

News

Especialistas do CCMAR vão otimizar produção e utilização de microalgas

O projeto chama-se ALGARED+ e o Centro de Ciências do Mar (CCMAR) é um dos membros do consórcio luso-espanhol de nove instituições que é responsável pelo projeto, que faz parte do Programa (POCTEP) Cooperação Transfronteiriça Espanha-Portugal.

Our researchers participated in the European Knowledge Hub about Food and Nutrition, where CCMAR is the only institution with experience in production and nutrition of micro and macroalgae.

In this event, the role of algae producing companies, new microalgae production strategies developed by LNEG, the concept of biorefinery of algal biomass and two round tables was presented.

Between the 6^th and 18^th of December 9 students of the Master in Marine Biology will defend their thesis.

During the three days of the congress, our researchers made several oral presentations and presented their posters.

Twelve young students from the high school participate in the internships that CCMAR offers in this year's edition, carried out by the CCVIVA - National Agency for Scientific Culture.

The Algae4IBD project, with CCMAR as a partner, aims to identify compounds from algae that are effective against inflammatory Bowel Disease and developing them into functional foods and new medication.

Our researchers have found that the use of LED lighting in the production of microalgae increases the growth of their biomass, especially during the night.

Publications

Year of Publication
2017	Pereira CGuerreiro, Barreira L, Bijttebier S, et al. Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis). Journal of Pharmaceutical and Biomedical Analysis. 2017;145. doi:10.1016/j.jpba.2017.07.007 Read more about Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis) Google Scholar DOI
2016	Rodrigues MJoão, Neves V, Martins A, et al. In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis). Food Chem. 2016;200:322-9. doi:10.1016/j.foodchem.2016.01.048 Read more about In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis). Google Scholar PubMed DOI
2016	Custódio L, Laukaityte S, Engelen AH, et al. A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal. Natural Product Research. 2016;30(6):724 - 728. doi:10.1080/14786419.2015.1040791 Read more about A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal Google Scholar DOI
2015	Vizetto-Duarte C, Pereira H, de Sousa CBruno, et al. Fatty acid profile of different species of algae of the Cystoseira genus: a nutraceutical perspective. Nat Prod Res. 2015;29(13):1264-70. doi:10.1080/14786419.2014.992343 Read more about Fatty acid profile of different species of algae of the Cystoseira genus: a nutraceutical perspective. Google Scholar PubMed DOI
2015	Grosso C, Cardoso ALúcia, Lemos A, et al. Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties. Eur J Med Chem. 2015;93:9-15. doi:10.1016/j.ejmech.2015.01.050 Read more about Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties. Google Scholar PubMed DOI
2015	Pereira H, Custódio L, Rodrigues MJoão, et al. Biological Activities and Chemical Composition of Methanolic Extracts of Selected Autochthonous Microalgae Strains from the Red Sea. Mar Drugs. 2015;13(6):3531-49. doi:10.3390/md13063531 Read more about Biological Activities and Chemical Composition of Methanolic Extracts of Selected Autochthonous Microalgae Strains from the Red Sea. Google Scholar PubMed DOI
2014	Rodrigues MJoão, Gangadhar KN, Vizetto-Duarte C, et al. Maritime halophyte species from southern Portugal as sources of bioactive molecules. Mar Drugs. 2014;12(4):2228-44. doi:10.3390/md12042228 Read more about Maritime halophyte species from southern Portugal as sources of bioactive molecules. Google Scholar PubMed DOI
2014	Schulze PSC, Barreira L, Pereira H, Perales JA, Varela J. Light emitting diodes (LEDs) applied to microalgal production. Trends Biotechnol. 2014;32(8):422-30. doi:10.1016/j.tibtech.2014.06.001 Read more about Light emitting diodes (LEDs) applied to microalgal production. Google Scholar PubMed DOI
2013	Martins DAlves, Custódio L, Barreira L, et al. Alternative sources of n-3 long-chain polyunsaturated fatty acids in marine microalgae. Mar Drugs. 2013;11(7):2259-81. doi:10.3390/md11072259 Read more about Alternative sources of n-3 long-chain polyunsaturated fatty acids in marine microalgae. Google Scholar PubMed DOI
2012	Hernández-Prieto MA, Schön V, Georg J, et al. Iron deprivation in Synechocystis: inference of pathways, non-coding RNAs, and regulatory elements from comprehensive expression profiling. G3 (Bethesda). 2012;2(12):1475-95. doi:10.1534/g3.112.003863 Read more about Iron deprivation in Synechocystis: inference of pathways, non-coding RNAs, and regulatory elements from comprehensive expression profiling. Google Scholar PubMed DOI
2012	Pereira H, Barreira L, Figueiredo F, et al. Polyunsaturated Fatty acids of marine macroalgae: potential for nutritional and pharmaceutical applications. Mar Drugs. 2012;10(9):1920-35. doi:10.3390/md10091920 Read more about Polyunsaturated Fatty acids of marine macroalgae: potential for nutritional and pharmaceutical applications. Google Scholar PubMed DOI
2011	Pereira H, Barreira L, Mozes A, et al. Microplate-based high throughput screening procedure for the isolation of lipid-rich marine microalgae. Biotechnol Biofuels. 2011;4(1):61. doi:10.1186/1754-6834-4-61 Read more about Microplate-based high throughput screening procedure for the isolation of lipid-rich marine microalgae. Google Scholar PubMed DOI
2009	Ramos AA, Marques AR, Rodrigues M, et al. Molecular and functional characterization of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Dunaliella salina. J Plant Physiol. 2009;166(9):968-77. doi:10.1016/j.jplph.2008.11.008 Read more about Molecular and functional characterization of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Dunaliella salina. Google Scholar PubMed DOI
2008	Coesel SNicole, Baumgartner ACordeiro, Teles LMarlene, et al. Nutrient limitation is the main regulatory factor for carotenoid accumulation and for Psy and Pds steady state transcript levels in Dunaliella salina (Chlorophyta) exposed to high light and salt stress. Mar Biotechnol (NY). 2008;10(5):602-11. doi:10.1007/s10126-008-9100-2 Read more about Nutrient limitation is the main regulatory factor for carotenoid accumulation and for Psy and Pds steady state transcript levels in Dunaliella salina (Chlorophyta) exposed to high light and salt stress. Google Scholar PubMed DOI
2008	Ramos AA, Varela J. Biochemistry and molecular biology in Portugal: an overview of past and current contributions. IUBMB Life. 2008;60(5):265-9. doi:10.1002/iub.65 Read more about Biochemistry and molecular biology in Portugal: an overview of past and current contributions. Google Scholar PubMed DOI
2008	Ramos AA, Coesel S, Marques A, et al. Isolation and characterization of a stress-inducible Dunaliella salina Lcy-beta gene encoding a functional lycopene beta-cyclase. Appl Microbiol Biotechnol. 2008;79(5):819-28. doi:10.1007/s00253-008-1492-4 Read more about Isolation and characterization of a stress-inducible Dunaliella salina Lcy-beta gene encoding a functional lycopene beta-cyclase. Google Scholar PubMed DOI

Supervising

Hugo Galvão Caiano Pereira

Galleries

João Varela

Organiza

Projects Coordination

Projects Membership

Especialistas do CCMAR vão otimizar produção e utilização de microalgas

CCMAR was specially selected to participate in the European Knowledge Hub about Food and Nutrition Security

Workshop Algae was a success

December: 9 MSc thesis defences at CCMAR

CCMAR researchers participated in the ALGAEUROPE congress

Summer internships entice young people to science

New research with algae brings hope for inflammatory bowel diseases

What are the benefits of LED lighting in microalgae cultivation?